FIELD: biotechnology.
SUBSTANCE: described is a composition suitable for treating haemophilia A, containing purified recombinant FVIII, obtained by a method for purifying or enriching the FVIII coagulation factor using chromatography. In one embodiment, the FVIII blood binding factor is obtained by chromatography, comprising the steps of: providing a fraction containing FVIII, bringing the fraction into contact with a cationic multimodal resin, washing the cationic multimodal resin with an aqueous wash buffer and eluting the fractions containing FVIII with an aqueous eluating buffer.
EFFECT: proposed invention extends the range of products for treating haemophilia A.
16 cl, 7 dwg, 22 tbl, 10 ex
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Authors
Dates
2019-08-26—Published
2009-06-24—Filed