FIELD: pharmaceuticals.
SUBSTANCE: invention relates to methyl 4-aryl-1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2,3-dioxo-2,3,5,10-tetrahydrobenzo[b]pyrrolo[2,3-e][1,4]diazepine-10a(1H)-carboxylates of the general formula
where Ar means Ph (IIIa), 4-MeOC6H4 (IIIb), 4-MeC6H4 (IIIc), 4-ClC6H4 (IIId) or 4-BrC6H4 (IIId). The invention also relates to a method of producing these compounds.
EFFECT: obtaining new compounds that can be used in medicine as agents with analgesic activity.
6 cl, 1 tbl, 6 ex
| Title |
Year |
Author |
Number |
| METHYL 3-AROYL-1-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-4-HYDROXY-5-OXO-2-CHLORO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLATES EXHIBITING ANTIMICROBIAL ACTIVITY, AND A METHOD FOR THEIR PREPARATION |
2022 |
- Denislamova Ekaterina Sergeevna
- Liadov Vadim Aleksandrovich
- Makrushin Dmitrii Evgenevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2792621C1 |
| METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-1,6-DIPHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-6-STYRYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHOD FOR PREPARING THEM |
2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| 1,1'-DIARYL-3'-AROYL-4'-HYDROXY-1H-SPIRO [INDENO[1,2-b]PYRROL-3,2'-PYRROL]-2,4,5'-(1'H)-TRIONES AND METHOD OF THEIR OBTAINING |
2011 |
- Bubnov Nikolaj Vladimirovich
- Denislamova Ekaterina Sergeevna
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467011C1 |
| ETHYL 1'-BENZYL-3,3-DIMETNYL-1,2'-DIOXO-5'-PHENYL-1'2,2',3,4,10-HEXAHYDRO-1H-SPIRO[ACRIDINE-9,3'-PYRROL]-4'-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2008 |
- Maslivets Andrej Nikolaevich
- Silajchev Pavel Sergeevich
- Makhmudov Ramiz Ragipovich
- Dmitriev Maksim Viktorovich
- Fedorovtseva Anastasija Nikolaevna
|
RU2387651C1 |
| ETHYL 3',7-DIOXO-5'-PHENYL-1,6-DIHYDRO-1'H-SPIRO{INDENO[1,2-b]QUINOLINE-6,3'-PYRROLE}-4'-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2010 |
- Dmitriev Maksim Viktorovich
- Makhmudov Ramiz Ragibovich
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
|
RU2453549C1 |
| METHYL 2,3,8-TRIOXO-4-PHENYLTETRAHYDRO-6H-PYRAZOLO[1,2-A]PYRROLO[2,3-C]PYRAZOLE-9A(1H)-CARBOXYLATES |
2019 |
- Maslivets Andrej Nikolaevich
- Dmitriev Maksim Viktorovich
- Makhmudov Ramiz Ragibovich
- Moroz Anna Andreevna
|
RU2721684C1 |
| 2-(6-ARYL-4-AROYL-3-METHYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDIN-5-YL)-2-OXO-N-ARYLACETAMIDES AND METHODS FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2501800C2 |
| (Z)-1'-R-6',6'-DIMETHYL-3-(PHENYL(ARYLAMINO)METHYLENE)-6',7'-DIHYDRO-3H-SPIRO[FURANE-2,3'-INDOL]-2',4,4',5(1'H,5'H)TETRAONS AND METHOD OF THEIR OBTAINING |
2008 |
- Maslivets Andrej Nikolaevich
- Silajchev Pavel Sergeevich
- Aliev Zajnutdin Gasanovich
|
RU2365592C1 |
| 1,6'-DIARYL-3-AROYL-4-HYDROXY-1',3'-DIMETHYLSPIRO[PIRROLE-2,5'-PYRROLO[2,3-d]PYRIMIDINE]-2',4',5(1H,1'H,3'H)-TRIONES AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2502738C2 |
| METHOD OF PRODUCING METHYL 1,7-DIARYL-9-AROYL-4-BENZOYL-3-HYDROXY-2,6-DIOXO-1,7-DIAZASPIRO[4,4]NONE-3,8-DIENE-8-CARBOXYLATES, EXHIBITING ANALGESIC ACTIVITY |
2013 |
- Denislamova Ekaterina Sergeevna
- Dubovtsev Aleksej Jur'Evich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2537999C1 |
