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2 792 621

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IPC

C07D403/04(2006-01-01)

A61K31/4155(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2022120658, 2022-07-28

(24)

Start date

2022-07-28

(22)

Actual filing date

2022-07-28

(45)

Published

2023-03-22

(72)

Inventor

Denislamova Ekaterina SergeevnaLiadov Vadim AleksandrovichMakrushin Dmitrii EvgenevichMaslivets Andrei NikolaevichBalandina Svetlana Iurevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Natsionalnyi Issledovatelskii Politekhnicheskii Universitet»

METHYL 3-AROYL-1-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-4-HYDROXY-5-OXO-2-CHLORO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLATES EXHIBITING ANTIMICROBIAL ACTIVITY, AND A METHOD FOR THEIR PREPARATION Russian patent published in 2023 - IPC C07D403/04 A61K31/4155 A61P31/04

Abstract RU 2792621 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to new compounds — methyl 3-aroyl-1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-hydroxy-5-oxo-2-chloro-2,5-dihydro-1H-pyrrole-2-carboxylates, where Ar means Ph (IIIa), 4-MeOC₆H₄ (IIIb), 4-MeC₆H₄ (IIIc), 4-ClC₆H₄ (IIId) or 4-BrC₆H₄ (IIIe), and the method of their preparation.

EFFECT: compounds have antimicrobial activity and can also be used for the synthesis of new heterocyclic compounds and medicinal products in pharmacology.

3 cl, 1 tbl, 6 ex

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RU 2 792 621 C1

Authors

Denislamova Ekaterina Sergeevna

Liadov Vadim Aleksandrovich

Makrushin Dmitrii Evgenevich

Maslivets Andrei Nikolaevich

Balandina Svetlana Iurevna

Dates

2023-03-22—Published

2022-07-28—Filed