METHOD OF DETERMINING CONTENT OF METALS IN LIQUID SAMPLES AND DEVICE FOR IMPLEMENTATION THEREOF Russian patent published in 2019 - IPC G01N21/03 G01N21/63 

FIELD: chemistry.

SUBSTANCE: invention relates to analytical chemistry, particularly to methods and apparatus for determining content of metals in liquid samples by atomic emission spectroscopy, can be used for early diagnosis of certain diseases and correction of treatment and recovery processes in the range of clinical laboratories. Essence of the disclosed solution lies in the fact that in the method of determining content of metals in liquid samples by preparing a sample, placing it in a microcuvette with an electrode in the lower part, placing above the microcircuit of the upper electrode, wherein the upper and lower electrodes are connected to each other, exciting the spark discharge between the sample in the microcap and the upper electrode, detecting the analytical signal of the emission radiation spectrum occurring at the moment of discharge, and determining the presence of metals in the sample on wavelengths and their concentrations from the luminescence intensity using the calibration curve, the upper electrode is in form of a rod of refractory metal with a pointed end, excitation of spark discharge is carried out by preliminary supply of constant high voltage to electrodes and subsequent approach of upper electrode end and upper meniscus of sample drop, continuous approach is carried out in the process of discharge until the capacitor is completely discharged, spectrum recording is started after current surge, recording emission spectrum is recorded in range of 200–1100 nm, simultaneously, luminous intensity and current in the discharge circuit are additionally recorded, wherein the analytical signal is the integral luminous intensity at the corresponding wavelength of the electromagnetic radiation in first 10–50 ms of the discharge with indent of 0.1–2 ms from the moment of the breakdown occurrence or the integral intensity, divided into the amount of electricity transmitted through the discharge, recorded during the luminous intensity recording period. Disclosed is a tablet analyzer for implementing the method.

EFFECT: technical result when implementing the declared group of solutions is the possibility of creating inexpensive express methods and devices suitable for direct determination of metals in small volumes of biological fluids of complex composition and process solutions.

6 cl, 4 dwg