FIELD: medicine.
SUBSTANCE: present group of inventions refers to medicine, namely to microbiology, molecular genetics and biotechnology, and concerns creation of live vaccine on the basis of strain Enterococcus faecium L3 for preventing and treating pneumonia caused by pneumococcal Streptococcus pneumoniae. For this purpose in structure of saws Eneterococcus faecium L3 include an antigen of a clinically relevant pathogenic microorganism. This is achieved by introducing a gene pspf pathogenic pneumococci into the chromosomal DNA of the probiotic strain Eneterococcus faecium L3.
EFFECT: vaccine created on the basis of a probiotic strain of microorganisms possesses evident immunogenic and protective effects that provides its effectiveness in relation to any serum pneumococcus.
3 cl, 12 dwg, 1 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR CREATING RECOMBINANT ENTEROCOCCUS L3-SARSN1 STRAIN BASED ON BIOLOGICALLY ACTIVE ENTEROCOCCUS FAECIUM L3 STRAIN | 2022 |
|
RU2820058C1 |
| METHOD OF CREATING A LIVE VACCINE AGAINST COVID-19 BASED ON THE PROBIOTIC STRAIN ENTEROCOCCUS FAECIUM L3 AND A LIVE VACCINE ENTEROCOCCUS FAECIUM L3-PENTF-COVID-19 | 2020 |
|
RU2745626C1 |
| METHOD FOR CREATING LIVE STRAIN OF ENTEROCOCCUS L3-SARS BASED ON BIOLOGICALLY ACTIVE STRAIN OF E. FAECIUM L3 | 2021 |
|
RU2782529C1 |
| METHOD FOR INTROGRESSION OF PATHOGENIC STREPTOCOCCUS GENES IN CHROMOSOMAL DNA OF PROBIOTIC STRAIN OF ENTEROCOCCUS FAECIUM L3 FOR EXPRESSION IN PILES | 2015 |
|
RU2640250C2 |
| INFLUENZA VIRUS STRAIN INFLUBACT-H7/PSPA FOR THE PRODUCTION OF A COMBINED VACCINE AGAINST INFLUENZA A VIRUS AND BACTERIAL PNEUMONIA CAUSED BY STREPTOCOCCUS PNEUMONIAE | 2021 |
|
RU2776196C1 |
| HYBRID PROTEIN VACCINE AGAINST PNEUMONIA CAUSED BY Streptococcus pneumoniae | 2012 |
|
RU2510281C2 |
| RECOMBINANT DNA ENSURING PRODUCTION OF THE RECOMBINANT PROTEIN COV1 EXHIBITING IMMUNOGENIC PROPERTIES AGAINST SARS-COV-2 VIRUS | 2021 |
|
RU2776484C1 |
| STRAIN OF Lactobacillus fermentum Z, USED FOR PRODUCTION OF PROBIOTIC CULTURED MILK FOODS | 2008 |
|
RU2412239C2 |
| ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS BASED ON BACTERIAL STRAIN | 2015 |
|
RU2616899C1 |
| ENTEROCOCCUS STRAIN ENTEROCOCCUS FAECIUM L-3 FOR THE TREATMENT AND PREVENTION OF BACTERIAL AND VIRAL INFECTIONS USING THERAPEUTIC AND PROPHYLACTIC AGENTS AND FOOD PRODUCTS MADE ON ITS BASIS AND A METHOD OF CULTIVATING THE ENTEROCOCCUS STRAIN ENTEROCOCCUS FAECIUM L-3 | 2022 |
|
RU2800359C1 |
