HYBRID PROTEIN VACCINE AGAINST PNEUMONIA CAUSED BY Streptococcus pneumoniae Russian patent published in 2014 - IPC A61K39/09 A61K39/112 C07K19/00 A61P31/04 

Abstract RU 2510281 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine. What is presented is a vaccine against pneumonia caused by Streptococcus pneumoniae, on the basis of a hybrid protein described by SEQ ID NO:1, containing fragments of the proteins Streptococcus pneumoniae PspA, Sprl 895, PsaA, as well as the ingredients of flagellin as an adjuvant, connected by flexible bridges.

EFFECT: invention provides the effective prevention and therapy of pneumonia ensured by the fact that the vaccine hybrid protein is composed of various immunogenic epitopes eliciting a specific immune response with formed immunological memory.

4 dwg, 8 ex

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RU 2 510 281 C2

Authors

Suvorov Aleksandr Nikolaevich

Dukhovlinov Il'Ja Vladimirovich

Orlov Anton Iosifovich

Bajguzin Evgenij Jakovlevich

Dates

2014-03-27Published

2012-06-22Filed