FIELD: pharmaceutics.
SUBSTANCE: present invention relates to the use of 6-((4-(2,3-dimethylphenoxy)piperidine-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione or its pharmaceutically acceptable salt for the treatment of a disease caused by a mycobacterial infection in a mammal, where the mycobacterial infection is Mycobacterium tuberculosis infection. Methods for the treatment of Mycobacterium tuberculosis mycobacterium infection, a combination including 6-((4-(2,3-dimethylphenoxy)piperidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione or its pharmaceutically acceptable salt and the second therapeutic agent, a pharmaceutical composition and a composition for use in the treatment of a disease caused by Mycobacterium tuberculosis mycobacterium infection, and a method for destroying mycobacterium and/or inhibiting mycobacterium replication in a mammal are also proposed.
EFFECT: implementation of a new application of 6-((4-(2,3-dimethylphenoxy)piperidine-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione or its pharmaceutically acceptable salt for the treatment of a disease caused by Mycobacterium tuberculosis infection.
21 cl, 11 ex
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