FIELD: chemistry.
SUBSTANCE: group of inventions relates to a rocuronium preparation. Injection preparation rocuronium in liquid form contains rocuronium and a buffer solution and has pH 3.5 or less, where the buffer solution is contained in concentration from 0.015 to 0.5 M and represents a buffer solution based on glycine and hydrochloric acid. Also disclosed is a method of increasing or improving the stability of an injectable rocuronium preparation and a method of preventing or reducing pain accompanying injection and vascular irritation caused by an injectable rocuronium preparation.
EFFECT: group of inventions provides higher stability of rocuronium preparation and reduced pain when injected.
8 cl, 1 dwg, 7 tbl, 12 ex
Authors
Dates
2019-11-13—Published
2014-06-26—Filed