ROCURONIUM PREPARATION WITH IMPROVED STABILITY Russian patent published in 2019 - IPC A61K31/568 A61K9/08 A61K47/06 A61P21/02 A61P23/00 

Abstract RU 2705996 C2

FIELD: chemistry.

SUBSTANCE: group of inventions relates to a rocuronium preparation. Injection preparation rocuronium in liquid form contains rocuronium and a buffer solution and has pH 3.5 or less, where the buffer solution is contained in concentration from 0.015 to 0.5 M and represents a buffer solution based on glycine and hydrochloric acid. Also disclosed is a method of increasing or improving the stability of an injectable rocuronium preparation and a method of preventing or reducing pain accompanying injection and vascular irritation caused by an injectable rocuronium preparation.

EFFECT: group of inventions provides higher stability of rocuronium preparation and reduced pain when injected.

8 cl, 1 dwg, 7 tbl, 12 ex

Similar patents RU2705996C2

Title Year Author Number
ROCURONIUM PREPARATION WITH IMPROVED STABILITY 2019
  • Itsuji, Yutaka
  • Nagahara, Hironori
  • Jinbo, Keisuke
RU2724900C1
ROCURONIUM PREPARATION WITH IMPROVED VASCULAR PAIN, METHOD FOR PRODUCING SAME, AND METHOD FOR SUPPRESSING AND/OR RELIEVING VASCULAR PAIN WHICH MAY BE CAUSED BY USE THEREOF 2014
  • Dzinbo, Kejsuke
  • Itsudzi, Yutaka
RU2680405C2
STABILIZED LIQUID COMPOSITIONS OF NEUROMUSCULAR BLOCKERS 2013
  • Khil Bekhar Khuan
  • Timoneda Ramia Kristina
RU2695226C2
COMPOSITION WITH HYALURONIC ACID AND METHOD FOR ITS PREPARATION 2022
  • Aksenov Anton Yurevich
  • Yudin Pavel Valerevich
RU2794886C1
INJECTION PREPARATION BASED ON DROTAVERINE AND PREPARATION METHOD THEREOF 2015
  • Borovikov Vitalij Eduardovich
RU2605826C1
PHARMACEUTICAL COMPOSITION 2011
  • Nilsson Anders
  • Malm Mattias
  • Wisniewski Kazimierz
  • Siekmann Britta
RU2604690C2
ANTI-PARASITIC COMPOSITION CONTAINING MACROCYCLIC LACTONE AND LEVAMISOLE, AND METHOD OF TREATING PARASITIC INFESTATION 2012
  • Lich Uejn Frederik
  • Alavi Fadil Al
  • Nanyan Kartigeyan
RU2591082C2
ANESTHETIC COMPOSITION AND METHOD OF EYE ANESTHETIZATION 2020
  • Uram, Martin
RU2812900C2
METHOD OF PREPARING THE PRESERVED MEDICINAL AGENT CONTAINING HUMAN PROTEIN FOR INJECTION OR INFUSION ADMINISTRATION 1992
  • Khajnrikh Voog[De]
  • Verner Gruber[De]
  • Khajns-Jorg Markl'[De]
  • Gerkhard Vinter[De]
  • Fritts Demmer[De]
RU2091068C1
PHARMACEUTICAL PREPARATIVE FORM 2004
  • Sangkhvi Suketu P.
  • Bojd Tomas A.
RU2362560C2

RU 2 705 996 C2

Authors

Itsuji, Yutaka

Nagahara, Hironori

Jinbo, Keisuke

Dates

2019-11-13Published

2014-06-26Filed