TRICYCLIC SPIRO COMPOUND Russian patent published in 2019 - IPC A61K31/277 A61K31/343 A61K31/353 A61K31/381 A61K31/397 A61K31/4025 A61K31/415 A61K31/4155 A61K31/4192 A61K31/422 A61K31/4245 A61K31/427 A61K31/437 A61K31/4418 A61K31/443 A61K31/4433 A61K31/4436 A61K31/4439 A61K31/453 A61K31/497 A61K31/501 A61K31/506 A61K31/5377 A61K31/5383 A61K31/382 A61K31/4406 A61K33/24 A61K39/395 A61K45/00 A61P1/02 A61P1/16 A61P1/18 A61P13/00 A61P19/08 A61P25/04 A61P35/00 A61P37/00 A61P43/00 A61P9/14 C07C255/58 C07D213/56 C07D231/12 C07D231/40 C07D307/94 C07D311/96 C07D405/04 C07D405/12 C07D405/14 C07D407/12 C07D409/04 C07D413/04 C07D413/12 C07D417/04 C07D417/12 C07D471/04 C07D498/04 

Abstract RU 2707073 C2

FIELD: chemistry.

SUBSTANCE: invention relates to EP4 receptor antagonist, which is a tricyclic spiro compound of general formula (I), or a pharmaceutically acceptable salt thereof, as well as to a pharmaceutical composition containing such a compound as an active ingredient, that is having EP4 receptor antagonist activity, for preventing and/or treating diseases caused by EP4 receptor activation.

EFFECT: disclosed is a tricyclic spiro compound.

20 cl, 1 dwg, 2 tbl, 142 ex

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RU 2 707 073 C2

Authors

Asada Masaki

Tani Kousuke

Hirobe Masaya

Higuchi Satonori

Fuchibe Kazuhiro

Oikawa Ryo

Kotani Tohru

Takano Hirotsugu

Dates

2019-11-22Published

2016-01-08Filed