PROTEIN TYROSIN PHOSPHATASE INHIBITORS Russian patent published in 2023 - IPC C07D401/14 C07D403/04 C07D451/04 C07D471/04 C07D471/10 C07D491/107 C07D513/10 C07D519/00 A61K31/53 A61P35/00 

Abstract RU 2799449 C2

FIELD: pharmaceutical chemistry.

SUBSTANCE: group of inventions includes triazine derivatives given in the claims, a medicinal product, a pharmaceutical composition, a method of inhibition and a method of treatment based on them, as well as their use.

EFFECT: triazine derivatives having SHP2 inhibitory activity and used for treatment of hyperproliferative disease associated with SHP2 activity.

17 cl, 4 tbl, 44 ex

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RU 2 799 449 C2

Authors

Blake, James F.

Boys, Mark Laurence

Chicarelli, Mark Joseph

Cook, Adam W.

Elsayed, Mohamed S. A.

Fell, Jay Bradford

Fischer, John P.

Hinklin, Ronald Jay

Jiang, Yutong

Mcnulty, Oren T.

Mejia, Macedonio J.

Rodriguez, Martha E.

Wong, Christina E.

Dates

2023-07-05Published

2020-03-30Filed