PHENYL DERIVATIVES Russian patent published in 2017 - IPC C07D205/04 C07D211/48 C07D211/52 C07D401/12 C07D405/12 A61K31/397 A61K31/445 A61K31/4523 A61K31/453 A61K31/4545 A61K31/5377 A61P9/00 A61P11/00 A61P25/00 

Abstract RU 2619105 C2

FIELD: chemistry.

SUBSTANCE: invention relates to new compounds of general formula

containing two cyclic groups, especially where M1 - Ring 1 and M2 - Ring 2, each independently represents a phenoxy group. The compounds have high antagonistic activity against human S1P2.

EFFECT: invention due to its properties can be used as a therapeutic agent for the treatment of S1P2-mediated diseases such as diseases, resulting from vasoconstriction, fibrosis and respiratory diseases.

8 cl, 6 dwg, 5 tbl, 45 ex

Similar patents RU2619105C2

Title Year Author Number
NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND MEDICAMENTS THEREOF AS ACTIVE INGREDIENT 2004
  • Nisizava Rena
  • Takaoka Josikazu
  • Sibajama Siro
RU2366655C2
DERIVATIVES OF CARBOXYLIC ACIDS AND PHARMACEUTICAL AGENT COMPRISING THEIR AS ACTIVE COMPONENT 2002
  • Tani Kosuke
  • Asada Masaki
  • Kobajasi Kaoru
  • Narita Masami
  • Ogava Mikio
RU2315746C2
INDOLE COMPOUND AND USE THEREOF 2006
  • Takeuti Dzun
  • Nakajama Josisuke
  • Fudzita Manabu
RU2416601C2
CARBOXYLIC ACID COMPOUNDS, PHARMACEUTICAL COMPOSITION BASED ON THEM, METHOD OF TREATMENT, AND APPLICATION 2004
  • Asada Masaki
  • Kobajasi Kaoru
  • Narita Masami
  • Sato Kazutojo
  • Kinosita Atsusi
  • Nagase Tosikhiko
  • Esikava Ken
RU2335490C2
PIPERIDINE DERIVATIVES AND AGENT COMPRISING PIPERIDINE DERIVATIVE AS ACTIVE COMPONENT 2001
  • Nakai Khisao
  • Kisikava Katsuja
RU2275359C2
N-PHENYLARYLSULFONYLAMIDE, PHARMACEUTICAL COMPOSITION CONTAINING INDICATED SUBSTANCE AS ACTIVE COMPONENT, COMPOUND AS INTERMEDIATE IN SYNTHESIS OF INDICATED COMPOUND AND METHOD FOR ITS PREPARING 2002
  • Naganava Atsusi
  • Saitokh Tetsudzi
  • Kobajasi Kaoru
  • Marujama Takajuki
  • Nakai Esikhiko
  • Khasimoto Sinsuke
RU2299202C2
NEW PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) 2005
  • Matsusima Tomokhiro
  • Takakhasi Kejko
  • Funasaka Setsuo
  • Obajsi Khirosi
RU2330021C2
COMPOUNDS BASED ON BENZOXAZINE AND INDOLE, WITH ANTAGONISTIC EFFECT ON cysLT RECEPTOR 2004
  • Takeuti Dzun
  • Itadani Satosi
  • Nakajama Josisuke
  • Tatsumi Tadasi
  • Takakhasi Sinia
  • Fudzita Manabu
RU2371436C2
NOVEL PYRIDINE DERIVATIVE AND DERIVATIVE OF PYRIMIDINE (3) 2006
  • Matsusima Tomokhiro
  • Takakhasi Kejko
  • Funasaka Setsuo
  • Obajsi Khirosi
  • Sirotori Sudzi
RU2362771C1
PEPTIDE COMPOUNDS 2001
  • Sima Itiro
  • Okhkava Takekhiko
  • Sato Kentaro
  • Isibasi Naoki
  • Imamura Kenitiro
RU2281955C2

RU 2 619 105 C2

Authors

Naganava Atsusi

Kusumi Kensuke

Otsuki Kazukhiro

Sekiguti Tetsuya

Kakuuti Akito

Sinodzaki Kodzi

Yamamoto Khirosi

Nonaka Sigeyuki

Dates

2017-05-12Published

2012-09-27Filed