FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology. A method provides genetic typing of a dog's DNA sample for the presence or absence of one or more polymorphisms specified in (a) SNP ATP7a_Reg3_F_6 (SEQ ID NO:142) and (b) one or more polymorphisms closely linked under non-equilibrium conditions to the above polymorphism in a dog's genome. What is also described is using the above polymorphisms to state a probability of the protection against accumulation of copper in the dog's liver or a propensity for accumulation of copper in the liver, as well as methods for selecting the dogs for breeding, and a method for preventing a disease related to accumulation of copper in the dog's copper. The presented group of inventions can be used in veterinary science.
EFFECT: what is presented is a method for dog testing to detect a probability of the protection against accumulation of copper in the dog's liver or the propensity for accumulation of copper in the liver.
15 cl, 11 dwg, 11 tbl, 9 ex
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