FIELD: chemistry.
SUBSTANCE: disclosed is a method of producing 2-(2-(4-fluorobenzoyl)phenylamino)-3-(4-(2-(9H-carbazol-9-yl)ethoxy)phenyl)propanoic acid, involving the following steps: (a) reacting compound (I) with compound (II) to obtain compound (III)
(b) hydrolysis of compound (III) to obtain compound (IV)
(c) acidifying compound (IV) with an acid to obtain 2-(2-(4-fluorobenzoyl)phenylamino)-3-(4-(2-(9H-carbazol-9-yl)ethoxy)phenyl)propanoic acid
wherein step (a) is carried out at temperature of 80 to 120 °C.
EFFECT: creation of large-scale industrial production of a method of producing 2-(2-(4-fluorobenzoyl)phenylamino)-3-(4-(2-(9H-carbazol-9-yl)ethoxy)phenyl)propanoic acid.
9 cl, 4 ex
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