FIELD: cosmetic industry.
SUBSTANCE: group of inventions refers to cosmetology and aims at reducing the appearance of dermatological signs of aging and developing sebum and/or reducing undesired lipogenesis or increasing lipolysis. Described is a composition and methods involving external application on skin of composition containing, in suitable for external application means of delivery, peptide, which includes: (a) the sequence QILSKLRL (SEQ ID NO: 5), LRLK (SEQ ID NO: 6) or MVV (SEQ ID NO: 7), or its salt, ester or pro-drug; (b) the TAKDGAP sequence (SEQ ID NO: 8), IFGGTVYRS (SEQ ID NO: 9) or RTPKISKPIKFELSG (SEQ ID NO: 10), or a salt thereof, an ester or pro-drug; or (c) the AECK sequence (SEQ ID NO: 11), or a salt thereof, an ester or pro-drug; wherein said prodrugs are N-acetyl derivative, N-acetyl side chain derivative, N-hydroxymethylated or N-phthalated derivative of its N-terminus and/or side chain.
EFFECT: group of inventions enables reducing signs of aging and/or improving skin health.
15 cl, 5 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDES FOR SKIN REJUVENATION AND METHODS OF THEIR USAGE | 2014 |
|
RU2666533C2 |
| COMPOSITIONS, CONTAINING CYCLIC PEPTIDES AND METHODS OF APPLYING THEREOF | 2009 |
|
RU2555357C2 |
| PEPTIDE FOR THE PREVENTION OF SKIN DAMAGE CAUSED BY ATMOSPHERIC POLLUTION AND FOR ANTI-AGING THERAPY, AS WELL AS ITS USE | 2019 |
|
RU2773534C1 |
| PEPTIDE INHIBITED FORMATION OF SNARE COMPLEX AND ITS USE | 2021 |
|
RU2812638C1 |
| PEPTIDE HAVING PROTECTIVE ACTIVITY AGAINST CELL DAMAGE CAUSED BY SOLID PARTICLES, AND USE THEREOF | 2020 |
|
RU2818535C1 |
| PEPTIDE PROTECTION AGAINST ULTRAVIOLET LIGHT TOXICITY | 2010 |
|
RU2565535C2 |
| NOVEL CELL PENETRATING PEPTIDE, CONJUGATE THEREOF WITH BOTULINUM TOXIN, AND USE THEREOF | 2015 |
|
RU2670135C2 |
| AMIDE-BASED PRODRUGS OF GLUCAGON SUPERFAMILY PEPTIDES | 2009 |
|
RU2550696C2 |
| PEPTIDES WITH PROTECTIVE ACTIVITY AGAINST CELL DAMAGE AND LIPOSOMAL FORMULATIONS | 2020 |
|
RU2833316C1 |
| SELECTIVE INHIBITORY PEPTIDES Nox-1 AND USE THEREOF | 2014 |
|
RU2699726C2 |
