IOHEXOL POWDER AND METHOD FOR USE THEREOF Russian patent published in 2020 - IPC A61K49/04 B01D3/36 

Abstract RU 2711501 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a contrast agent containing particles of iohexol (embodiments) crystals as a contrast agent, and to a method of producing said particles of iohexol crystals. In the first embodiment, particles of iohexol crystals have bulk density of less than 0.8 g/cm3, free space between particles of more than 60 % of bulk volume and specific surface area of more than 0.8 m2/g. In the second embodiment, particles of iohexol crystals are characterized by a powder X-ray diffraction pattern having peaks 2θ at 7.6°, 16.2°, 19.9°, 20.8°, 22.3°, 29.8° and 30.7°.

EFFECT: invention increases solubility of particles of iohexol.

15 cl, 6 ex, 4 tbl, 15 dwg

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RU 2 711 501 C2

Authors

Prokop, Jiri

Hlavacek, Ivan

Zahradnlk, Petr

Malinak, Jiri

Dates

2020-01-17Published

2015-03-04Filed