FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and concerns a composition for binding to rabies virus glycoprotein (RVGP), which is a mixture of two neutralizing antibodies, human mAT RabD4 and humanised mAT 1S5. Group of inventions also relates to a pharmaceutical composition for pre- and post exposure prevention of rabies, characterized by that it includes said antibody composition and a pharmaceutically acceptable carrier.
EFFECT: group of inventions prevents prevention of individual mutant versions of rabies virus from neutralization.
8 cl, 3 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEUTRALIZING MONOCLONAL ANTIBODY BINDING TO RABIES VIRUS GLYCOPROTEIN G, DNA FRAGMENTS CODING SAID ANTIBODY, AND ANTIGEN-BINDING FRAGMENT | 2017 |
|
RU2718835C2 |
| HUMANISED ANTIGEN-BINDING FRAGMENTS (Fab) AGAINST RABIES VIRUS, ISOLATED DNA FRAGMENT, CODING Fab AGAINST RABIES VIRUS, YEAST CELL, TRANSFORMED BY DNA FRAGMENT, AND METHOD OF OBTAINING Fab AGAINST RABIES VIRUS WITH APPLICATION OF YEASTS | 2010 |
|
RU2440412C2 |
| PHARMACEUTICAL COMPOSITION FOR PASSIVE RABIES IMMUNIZATION, PHARMACEUTICAL KIT, PHARMACEUTICAL KIT APPLICATION METHOD | 2016 |
|
RU2661028C2 |
| ANTIGEN BINDING SECTION (FAB), INCLUDING HUMANIZED FAB, AGAINST BOTULINICAL NEUROTOXIN C (VERSIONS), METHOD TO OBTAIN FAB USING YEAST, METHOD AND SET FOR BOTULINICAL NEUROTOXIN C DETECTION | 2016 |
|
RU2623157C1 |
| HUMANISED 5D3HU ANTIBODY BINDING TO THE PRAME TUMOUR ANTIGEN, DNA FRAGMENTS ENCODING SAID ANTIBODY, AND ANTIGEN-BINDING FRAGMENT OF THE ANTIBODY | 2020 |
|
RU2761876C1 |
| HUMANIZED ANTIBODY 6H8HU, BINDING TO TUMOUR ANTIGEN PRAME, DNA FRAGMENTS CODING SAID ANTIBODY AND ANTIGEN-BINDING ANTIBODY FRAGMENT | 2020 |
|
RU2768737C1 |
| HUMANISED NEUTRALIZING ANTIBODY TO HUMAN INTERFERON-BETA | 2019 |
|
RU2737466C1 |
| MONOCLONAL ANTIBODY, BINDING WITH EBOLA VIRUS GLYCOPROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY, AND ANTIGEN-BINDING FRAGMENT | 2015 |
|
RU2639533C2 |
| MONOCLONAL ANTIBODY, LINKING WITH E-BIR VIRUS GLOBE-PROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY AND ANTIGEN-BINDING FRAGMENT | 2016 |
|
RU2644334C2 |
| MONOCLONAL ANTIBODY, BINDING WITH EBOLA VIRUS GLYCOPROTEIN, DNA FRAGMENTS CODING THIS ANTIBODY, AND ANTIGEN-BINDING FRAGMENT | 2015 |
|
RU2630304C2 |
