FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental pharmacology, and can be used to simulate thermal skin injury of degree IIIA in a rat with pre-prepared skin areas under ether anesthesia. Skin is thermally affected for 10 seconds with the bottom of a dry flat-bottomed test tube 18 mm in diameter, filled with boiling water at 100 °C, containing a load and having total weight of 132.5 g, in the projection of the lower part of the blade symmetrically on both sides of the body. Burns are applied alternately, with repeated heating of the test tube before the second burn.
EFFECT: method provides creating a model of burn injury IIIA degree due to identical in all involved in experiments of rats, adequate clinical conditions of skin lesions without damaging viability of subcutaneous muscles.
1 cl, 2 dwg
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