LIPOSOMAL DRUG FOR TREATING LOCAL RADIATION DAMAGES OF SKIN Russian patent published in 2020 - IPC A61K38/17 A61K35/16 A61K47/24 A61K47/10 A61K47/14 A61K9/127 A61P17/02 

Abstract RU 2712079 C1

FIELD: pharmaceutics.

SUBSTANCE: invention refers to pharmaceutics, particularly to agents for treating local radiation damages of skin. Medicinal agent according to the invention in the form of liposomes includes an aqueous solution of recombinant human alpha-fetoprotein (rchAFP) with its content in amount of not less than 1.0 mg/ml, solution of phospholipids Lipoid S80 in propylene glycol, preserving agents – methyl paraben and propylparaben, and butylhydroxytoluene, in quantities specified in the patent claim.

EFFECT: according to the invention, the liposomal drug is stable during storage and is characterized by high aggregation resistance both during manufacture and storage.

1 cl, 3 dwg, 5 tbl

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RU 2 712 079 C1

Authors

Akleev Andrej Aleksandrovich

Pryakhin Evgenij Aleksandrovich

Tryapitsyna Galina Aleksandrovna

Atamanyuk Natalya Igorevna

Shaposhnikova Irina Aleksandrovna

Ostroumov Yurij Igorevich

Semenkova Lidiya Nikolaevna

Dudich Igor Vyacheslavovich

Grebennikov Evgenij Petrovich

Shmelin Pavel Sergeevich

Dates

2020-01-24Published

2019-09-05Filed