PYRIDINES, PYRIMIDINES AND PYRAZINES AS BRUTON'S TYROSINE KINASE INHIBITORS AND USE THEREOF Russian patent published in 2020 - IPC C07D487/04 A61K31/519 A61P29/00 

Abstract RU 2712220 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to compounds of formula I and their pharmaceutically acceptable compositions.

EFFECT: technical result is obtaining novel compounds suitable as Bruton tyrosine kinase inhibitors, which can be used to produce medicinal agents for preventive or therapeutic treatment of mediated disorder.

11 cl, 1 tbl, 81 ex

Similar patents RU2712220C2

Title Year Author Number
HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USE THEREOF 2014
  • Tsyu Khoj
  • Koldvell Richard D.
  • Neagu Konstantin
  • Mochalkin Igor
  • Lyu-Budzhalski Lesli
  • Dzhouns Rejnaldo
  • Tate Devon
  • Dzhonson Tereza L.
  • Gardberg Anna
RU2703301C2
PRIMARY CARBOXAMIDES AS BTK INHIBITORS 2014
  • Bonafu Dominik
  • Devis Khiter M.
  • Frenk Kristin E.
  • Fridman Majkl M.
  • Kherold Dzh. Martin
  • Khoumann Majkl Z.
  • Khantli Rejmond
  • Osuma Ogastin
  • Sheppard Dzhordzh
  • Somal Gagandip K.
  • Van Kamp Dzhennifer
  • Van Epps Stejsi A.
  • Vasudevan Anil
  • Uollejs Grir A.
  • Van Lu
  • Van Lu
  • Van Chzhi
  • Uilson Noel S.
  • Syuj Syandun
RU2708395C2
PYRIMIDINE DERIVATIVES AS BTK INHIBITORS AND USE THEREOF 2016
  • Qiu, Hui
  • Caldwell, Richard D.
  • Liu-Bujalski, Lesley
RU2743040C2
SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 2018
  • Larsen, Jens
RU2817698C2
6-[4-(1H-IMIDAZOL-2-YL)PIPERIDIN-1-YL]PYRIMIDIN-4-AMINE DERIVATIVES AS MODULATORS OF KINASE ACTIVITY 2014
  • Lan Zhosi
  • Chen Syaolin
  • Syao Yujfan
  • Khak Bajard R.
  • Goutopoulos Andreas
RU2674261C2
COMPOUNDS OF TETRAHYDROPYRASOLOPIRIMIDINE 2013
  • Khokins Linn D.
  • Buaven Rosh
  • Karlson Erik
  • Endo Atsusi
  • Khansen Khans
  • Isizaka Salli
  • Makki Mettyu
  • Narayan Sridkhar
  • Satokh Takasi
  • Shiller Shon
RU2677291C2
PYRROLOPYRIMIDINE COMPOUNDS FOR MALIGNANT TUMOUR TREATMENT 2012
  • Wang Xiaodong
  • Liu Jing
  • Zhang Weihe
  • Frye Stephen
  • Kireev Dmitri
RU2631655C2
METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS, USING PYRIMIDINE AND PYRIDINE COMPOUNDS WITH BTK-INHIBITING ACTIVITY 2016
  • Dellovade Tammy
RU2779287C2
BRUTON'S TYROSINE KINASE INHIBITORS 2013
  • Bagirat Niala
  • Dominik Romir
  • Kennedi-Smit Dzhoshua
  • Lopez-Tapia Fransisko Khaver
  • Mertts Erik
  • Tsyao Tsi
  • So Sun-Sau
RU2619465C2
CERTAIN CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS 2014
  • Tsyan Syanpin
  • Chzhu Jong-Lyan
RU2718876C2

RU 2 712 220 C2

Authors

Lyu-Budzhalski Lesli

Ngujen Ngan

Tsyu Khoj

Dzhouns Rejnaldo

Mochalkin Igor

Koldvell Richard D.

Dates

2020-01-27Published

2014-07-30Filed