METHOD OF PRODUCING N,O-COMPLEXES OF {2-[(DIMETHYLAMINO)METHYL]PHENOL} COPPER (II) DIACETATE, HAVING FUNGICIDAL ACTIVITY AGAINST CANDIDA ALBICANS Russian patent published in 2020 - IPC C07F1/08 A61K31/30 

Abstract RU 2714320 C1

FIELD: chemistry.

SUBSTANCE: present invention relates to a method of producing N,O-complexes of {2-[(dimethylamino)methyl]phenol} copper (II) diacetate (1):

involving reaction of bidentate 2-[(dimethylamino)methyl]phenol, where R=H, O-Prn, 3.5-(CH3)2, 4-But, with equimolar amount of copper (II) diacetate monohydrate in ethanol medium at room temperature (~20 °C) and atmospheric pressure for 2–4 hours. Also disclosed is use of obtained complex.

EFFECT: disclosed complex can be used as an agent possessing fungicidal activity against Candida albicans fungi.

2 cl, 2 tbl, 1 ex

Similar patents RU2714320C1

Title Year Author Number
METHOD OF PRODUCING BINUCLEAR N,O-COMPLEXES OF DIACETATE MONOHYDRATE (DIHYDRATE DICHLORIDE, DIBROMIDE) COPPER (II) WITH 1-[(DIMETHYLAMINO) METHYL]-2-NAPHTHOL, HAVING FUNGICIDAL ACTIVITY 2019
  • Akhmetova Vnira Rakhimovna
  • Bikbulatova Elmira Minurovna
  • Akhmadiev Nail Salavatovich
  • Abdullina Zilya Yamilovna
  • Ibragimov Askhat Gabdrakhmanovich
  • Dzhemilev Usein Memetovich
RU2726651C1
MONO- AND BINUCLEAR N,O-COMPLEXES OF COPPER (II) DIACETATE WITH 1-[(DIMETHYLAMINO) METHYL]-2-NAPHTHOL, HAVING ANTI-TUMOUR ACTIVITY 2020
  • Akhmetova Vnira Rakhimovna
  • Bikbulatova Elmira Minurovna
  • Akhmadiev Nail Salavatovich
  • Dyakonov Vladimir Anatolevich
  • Dzhemileva Lilya Useinovna
  • Ibragimov Askhat Gabdrakhmanovich
  • Dzhemilev Usein Memetovich
RU2739317C1
N,N-COMPLEXES OF DICHLORODI-[3,5-DIMETHYL-4-(SULPHANYLMETHYL)-1H-PYRAZOLE]DIHYDRATE OF COPPER (II), HAVING FUNGICIDAL ACTIVITY AGAINST CANDIDA ALBICANS FUNGUS 2017
  • Akhmetova Vnira Rakhimovna
  • Akhmadiev Nail Salavatovich
  • Nurtdinova Galiya Maratovna
  • Ibragimov Askhat Gabdrakhmanovich
  • Dzhemilev Usein Memetovich
RU2708086C2
POLYNUCLEAR BILIGAND N,O-COMPLEXES OF PALLADIUM (II) AND PLATINUM (II) WITH 1-[(DIMETHYLAMINO)METHYL]-2-NAPHTHOL, METHOD FOR PRODUCTION AND USE THEREOF AS AGENTS HAVING ANTICANCER ACTIVITY 2021
  • Akhmetova Vnira Rakhimovna
  • Bikbulatova Elmira Minurovna
  • Akhmadiev Nail Salavatovich
  • Dyakonov Vladimir Anatolevich
  • Dzhemileva Lilya Useinovna
RU2767457C1
APPLICATION OF AROMATIC AZOMETHINES WITH HIGHER ALKYL SUBSTITUENTS AS MEANS OF BACTERICIDAL AND FUNGICIDAL ACTIVITY 2016
  • Galkina Irina Vasilevna
  • Bakhtiyarova Yuliya Valerevna
  • Gerasimov Aleksandr Vladimirovich
  • Shulaeva Marina Petrovna
  • Pozdeev Oskar Kimovich
  • Galkin Vladimir Ivanovich
RU2640816C2
COMPLEXES OF COPPER (II) AND NICKEL (II) WITH 1-(β-HYDROXYETHYL)-2-METHYL-5-NITROIMIDAZOLE 1997
  • Kaletina N.I.
  • Kokornikova O.F.
  • Afanas'Ev Ju.I.
  • Arzamastsev E.V.
  • Rubinov G.E.
  • Zakharova V.F.
  • Bel'Tjukova A.G.
  • Baryshnikov A.Ju.
  • Kaletin G.I.
RU2098421C1
PHOSPHORYL-CONTAINING QUATERNARY AMMONIUM SALTS WITH HIGHER ALKYL SUBSTITUENTS WITH BACTERICIDAL AND FUNGICIDAL ACTIVITY 2021
  • Davletshin Rustam Rifkhatovich
  • Gaineev Aidar Maratovich
  • Galkina Irina Vasilevna
  • Davletshina Natalia Viktorovna
  • Shulaeva Marina Petrovna
  • Pozdeev Oskar Kimovich
RU2770537C1
COMPOUNDS OF HYPERBRANCHED POLYMER Boltorn H COMPLEXES POSSESSING ANTI-CANDIDA ACTIVITY AND METHOD FOR PREPARING THEM 2010
  • Ulakhovich Nikolaj Alekseevich
  • Kutyreva Marianna Petrovna
  • Usmanova Gul'Naz Shamilevna
RU2478106C2
METHOD FOR PRODUCING N,N-COMPLEXES OF DICHLORODI-[3,5-DIMETHYL-4-(SULFANYLMETHYL)-1H-PYRAZOLE]COPPER DIHYDRATE (II) 2017
  • Akhmetova Vnira Rakhimovna
  • Akhmadiev Nail Salavatovich
  • Nurtdinova Galiya Maratovna
  • Khisamutdinov Ravil Akhmetzyanovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Dzhemilev Usein Memetovich
RU2677484C2
METHOD OF PRODUCING 1-(3-HYDROXY, 28-ACETOXY-LIP-20(29)-EN-30-YL)-PYRIDINIUM BROMIDE AND USE THEREOF AS AN AGENT WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY 2018
  • Parfenova Lyudmila Vyacheslavovna
  • Shakurova Elvira Rifovna
  • Ponedelkina Irina Yurevna
RU2725873C2

RU 2 714 320 C1

Authors

Akhmetova Vnira Rakhimovna

Bikbulatova Elmira Minurovna

Akhmadiev Nail Salavatovich

Ibragimov Askhat Gabdrakhmanovich

Dzhemilev Usein Memetovich

Dates

2020-02-14Published

2019-05-14Filed