FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to reproduction of human diseases in experiment, and can be used for simulation of blood coagulation system disorders with cytostatic action background. Cisplatin is introduced intraperitoneally once into mice at 10 mg/kg, rats 4 mg/kg, on 10th day after cisplatin administration, blood is taken and the coagulation hemostasis link activity is analyzed.
EFFECT: method provides a clinical picture of a thrombosis when reproducing disorders of the hemostasis system due to the use of anticancer preparations by administering cisplatin.
1 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF MODELING HEMOSTASIS DISORDERS IN COMBINED LUNG LESIONS WITH BACTERIAL INFLAMMATION AND PULMONARY VASCULAR THROMBOSIS | 2023 |
|
RU2800645C1 |
| METHOD FOR CORRECTING HYPERCOAGULABLE STATE WHEN ANTITUMOR DRUG CISPLATIN IS ADMINISTERED BY INJECTION | 2020 |
|
RU2743848C1 |
| METHOD FOR ENHANCING ANTIMETASTATIC ACTION OF CISPLATIN AND REDUCING ITS SIDE EFFECT ON HAEMOSTASIS SYSTEM | 2023 |
|
RU2825825C1 |
| METHOD OF MODELING OF CHRONIC COAGULOPATHY IN EXPERIMENTAL ANIMALS | 2020 |
|
RU2746831C1 |
| METHOD OF CORRECTING THROMBOSIS WITH RESVERATROL IN AN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2722273C1 |
| METHOD OF MODELING CHRONIC TOXIC COAGULOPATHY IN RATS | 2023 |
|
RU2800860C1 |
| METHOD OF CORRECTING THROMBOSIS BY NICORANDIL IN AN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2721291C1 |
| METHOD FOR MODELING CHRONIC TOXIC COAGULOPATHY IN EXPERIMENTAL ANIMALS | 2017 |
|
RU2661722C1 |
| METHOD FOR HOMEOSTATIC DISORDER CORRECTION IN CHILDREN WITH HEPATIC HEMANGIOMAS | 2012 |
|
RU2483737C1 |
| METHOD FOR PREVENTING CHRONIC MOLYBDENUM COAGULOPATHY | 2020 |
|
RU2739690C1 |
