FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental pharmacology, and can be used for correction of thrombosis in ADMA-like model of preeclampsia. That is ensured by reproducing a model of experimental ADMA-like preeclampsia in Wistar rats. Thrombosis is corrected by oral administration of Nicorandil at dose of 10 mg/kg twice day from 14th to 20th day of pregnancy.
EFFECT: method provides marked thrombosis correction in a simulated pathology manifested by increased time of thrombosis.
1 cl, 1 tbl, 1 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF CORRECTING THROMBOSIS WITH RESVERATROL IN AN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2722273C1 |
METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION IN AN ADMA-LIKE MODEL OF PREECLAMPSIA USING ACETYLSALICYLIC ACID | 2019 |
|
RU2721290C1 |
METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION IN ADMA-LIKE MODEL OF PREECLAMPSIA USING DETRALEX | 2019 |
|
RU2723453C1 |
METHOD OF CORRECTION OF PLACENTAL MICROCIRCULATION DISORDERS WITH USING DETRALEX | 2019 |
|
RU2727572C1 |
METHOD OF CORRECTION OF PLACENTAL MICROCIRCULATION DISORDERS WITH 2-HYDROXYPHENYLTHIOACETAMIDE DERIVATIVES | 2019 |
|
RU2721554C1 |
METHOD OF CORRECTING MORPHOLOGICAL CHANGES IN PLACENTA WITH SUBSTANCE OF 3-HYDROXY-2-ETHYL-6-METHYLPYRIDINIUM NICOTINATE IN ADMA-LIKE MODEL OF PREECLAMPSIA | 2020 |
|
RU2735765C1 |
METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION WITH CARBAMYLATED DARBEPOETIN IN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2707057C1 |
METHOD OF CORRECTING ENDOTHELIAL DYSFUNCTION WITH TRIMETAZIDINE IN AN ADMA-LIKE MODEL OF PREECLAMPSIA | 2018 |
|
RU2700563C1 |
METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION WITH ASIALISED ERYTHROPOIETIN IN AN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2707060C1 |
METHOD OF CORRECTION OF MICROCIRCULATION DISORDERS IN PLACENTA WITH CARBAMYLATED DARBEPOETIN IN ADMA-LIKE MODEL OF PREECLAMPSIA | 2019 |
|
RU2720103C1 |
Authors
Dates
2020-05-18—Published
2019-11-08—Filed