METHOD FOR ASSESSMENT OF SEVERITY OF INFECTIOUS PROCESS IN UROGENITAL INFECTION IN PREGNANT WOMEN Russian patent published in 2020 - IPC C12Q1/68 C12N15/00 

FIELD: biotechnology.

SUBSTANCE: invention refers to biotechnology, namely to obstetrics, gynecology, infectious pathology and immunology, and can be used in prediction of pregnancy outcome in urogenital infection. In pregnant women with UTI in scraper material from mucous membranes of cervical canal and / or vagina, EG levels of TLR2 and TLR8 are established by real-time polymerase chain reaction (PCR RT) with reverse transcription (OT-Real-Time PCR). To assess severity of infectious process values of classification functions are calculated by formulas, and obtained using formulas criterions of classification linear functions of discriminator analysis F₁ and F₂ are rounded to second decimal place (to hundredths) and maximum value of function is established. If observing the maximum value F₁, the acute course of the infectious process is established, while maximum F₂ value is used to establish the chronic course of the infectious process.

EFFECT: invention involves a method for early informative assessment of the severity of the infectious process in pregnant women according to classification rules of linear discriminant analysis of EG TLRs.

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