FIELD: biotechnology.
SUBSTANCE: biosynthetic gene cluster includes 44 open gene reading frames (GRF): 5 GRF (GRF 10-14) encoding the polyketide synthase; 9 GRF (GRF 1, 4–6, 15 and 36–39) related to unit for synthesis and modification of polyketone; 16 GRF (GRF 9, 16–22, 24, 26, 28, 29, 33–35 and 41) related to synthesis of glycosyl; 6 GRF (GRF 7, 8, 30–32 and 40) related to glycosyl transfer; 2 GRF (GRF 3 and 25) related to resistance; 4 GRF (GRF 2, 23, 27 and 42) probably related to regulation; GRF of thiosteprone-resistant marker gene (GRF 43); and GRF of 4''-miscarose-glucoside-isovaleryl-transferase (GRF 44) gene.
EFFECT: invention relates to biotechnology and represents a biosynthetic gene cluster of carrimycin.
10 cl, 6 dwg, 2 tbl, 4 ex
| Title |
Year |
Author |
Number |
| POLYNUCLEOTIDE CODING ACYLTRANSFERASE THAT RESPONDS FOR MODIFICATION OF PLATENOLID IN POSITION 3 (VERSIONS), POLYPEPTIDE THAT REPRESENTS ACYLTRANSFERASE, WHICH IS RESPONSIBLE FOR MODIFICATION OF PLATENOLID IN POSITION 3 (VERSIONS), BACTERIAL EXPRESSION VECTOR (VERSIONS), BACTERIAL EXPRESSION SYSTEM, BACTERIAL HOST CELL, METHOD FOR PRODUCTION OF POLYPEPTIDE, STRAIN STREPTOMYCES AMBOFACIENS, APPLICATION OF POLYNUCLEOTIDE (VERSIONS), CELL OF BACTERIUM STREPTOMYCES AMBOFACIENS, HOST CELL STREPTOMYCES AMBOFACIENS AND METHOD OF POLYPEPTIDE PRODUCTION |
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