DYNAMIC CYCLIC AMINE AND PHARMACEUTICAL APPLICATION THEREOF Russian patent published in 2018 - IPC C07D401/06 C07D403/06 A61K31/4178 A61K31/454 A61K31/496 A61P25/04 A61P29/02 

Abstract RU 2667062 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely a cyclic amine derivative or a pharmacologically acceptable salt thereof of general formula (I), wherein the carbon atom marked with * is an asymmetric carbon atom and A is a group represented by the general formula (IIa), (IIb) or (IIc), where R1 is a methyl group or an ethyl group optionally substituted by a halogen atom, R2 represents a hydrogen atom or an alkylcarbonyl group having from 2 to 5 carbon atoms, each R3 independently represents a methyl group or an ethyl group, and n is 1 or 2. Invention also relates to a medicament, an analgesic and a therapeutic agent based on a compound of formula (I). , .

EFFECT: cyclic amine derivative having an analgesic effect is obtained, in particular with respect to neuropathic pain and/or fibromyalgia syndrome.

10 cl, 18 dwg, 8 tbl, 19 ex

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RU 2 667 062 C1

Authors

Arai, Tadamasa

Morita, Yasuhiro

Udagawa, Shuji

Iseki, Katsuhiko

Izumimoto, Naoki

Dates

2018-09-14Published

2016-02-26Filed