FIELD: chemistry.
SUBSTANCE: invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is -O- or -CH2-, n from 1 to 3, R1 is -H, halogen or lower alkyl, R2 and R3 are each the same or different from each other and are -H, halogen, lower alkyl or halo-lower alkyl, R4 is -Lk-NH-R0, Lk is lower alkylene or bond, R0 is lowest alkyl, lower alkylene-OH or cycloalkyl, and R5 is -H or lower alkyl. Invention also relates to a pharmaceutical composition having IK1 channel activating action.
(I).
EFFECT: obtained are novel compounds that can be used in medicine for the treatment of visceral pain, inflammatory pain, osteoarthritis pain, neuropathic pain or fibromyalgia.
17 cl, 26 tbl, 31 ex
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