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(11)

2 720 767

(13)

(51)

IPC

C12Q1/6816(2018-01-01)

C12Q1/6844(2018-01-01)

C12Q1/6876(2018-01-01)

C12Q1/6888(2018-01-01)

C12N15/11(2006-01-01)

C12N15/113(2010-01-01)

C12N9/22(2006-01-01)

(21) (22)

Application

2019141298, 2019-12-13

(24)

Start date

2019-12-13

(22)

Actual filing date

2019-12-13

(45)

Published

2020-05-13

(72)

Inventor

Akimkin Vasilij GennadevichTyumentsev Aleksandr IgorevichTyumentseva Marina Alekseevna

(73)

Holder

Federalnoe Byudzhetnoe Uchrezhdenie Nauki Nauchno-Issledovatelskij Institut Epidemiologii» Federalnoj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchiya Cheloveka Tsnii Epidemiologii Rospotrebnadzora)

METHOD FOR DETECTING PROVIRAL DNA OF HUMAN IMMUNODEFICIENCY VIRUS INTEGRATED INTO HUMAN GENOME IN ULTRALOW CONCENTRATIONS AND SPECIFIC OLIGONUCLEOTIDES FOR USE IN METHOD Russian patent published in 2020 - IPC C12Q1/6816 C12Q1/6844 C12Q1/6876 C12Q1/6888 C12N15/11 C12N15/113 C12N9/22

Abstract RU 2720767 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to RNA guides, ribonucleoprotein complexes of CRISPR / CAS system containing RNA guides, and sets containing ribonucleoprotein complexes of CRISPR / CAS system and specific oligonucleotides for pre-amplification of highly conserved areas of HIV-1 genome. Invention enables efficient detection of proviral DNA of HIV-1 after specific amplification of DNA fragments of HIV-1.

EFFECT: invention provides detecting single copies of proviral DNA of human immunodeficiency virus (HIV-1) integrated into the human genome.

5 cl, 11 dwg, 4 tbl, 5 ex

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RU 2 720 767 C1

Authors

Akimkin Vasilij Gennadevich

Tyumentsev Aleksandr Igorevich

Tyumentseva Marina Alekseevna

Dates

2020-05-13—Published

2019-12-13—Filed