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(13)

(51)

IPC

C12N15/11(2006-01-01)

C12N15/113(2010-01-01)

C12N9/22(2006-01-01)

C12Q1/6816(2018-01-01)

C12Q1/6844(2018-01-01)

C12Q1/6876(2018-01-01)

C12Q1/6888(2018-01-01)

(21) (22)

Application

2019141293, 2019-12-13

(24)

Start date

2019-12-13

(22)

Actual filing date

2019-12-13

(45)

Published

2020-05-13

(72)

Inventor

Akimkin Vasilij GennadevichTyumentsev Aleksandr IgorevichTyumentseva Marina Alekseevna

(73)

Holder

Federalnoe Byudzhetnoe Uchrezhdenie Nauki Nauchno-Issledovatelskij Institut Epidemiologii" Federalnoj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchiya Cheloveka Tsnii Epidemiologii Rospotrebnadzora)

CRISPR-CAS SYSTEM FOR DETECTING PROVIRAL DNA OF HUMAN IMMUNODEFICIENCY VIRUS INTEGRATED INTO A HUMAN GENOME IN ULTRA-LOW CONCENTRATIONS Russian patent published in 2020 - IPC C12N15/11 C12N15/113 C12N9/22 C12Q1/6816 C12Q1/6844 C12Q1/6876 C12Q1/6888

Abstract RU 2720768 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to RNA guides, ribonucleoprotein complexes of CRISPR / CAS system containing RNA guides, and sets containing ribonucleoprotein complexes of CRISPR / CAS system and specific oligonucleotides for preliminary amplification of highly conserved HIV-1 genome areas. Invention enables efficient detection of proviral HIV-1 DNA after specific amplification of HIV-1 DNA fragments.

EFFECT: invention provides detecting single copies of proviral DNA of human immunodeficiency virus (HIV-1) integrated into the human genome.

7 cl, 11 dwg, 4 tbl, 5 ex

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RU 2 720 768 C1

Authors

Akimkin Vasilij Gennadevich

Tyumentsev Aleksandr Igorevich

Tyumentseva Marina Alekseevna

Dates

2020-05-13—Published

2019-12-13—Filed