FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to medicine and pharmacy. Disclosed is a combined medicinal preparation for treating type 2 diabetes and dyslipidemia in diabetic patients, comprising a peptidase IV inhibitor gemigliptin or its salt, an inhibitor of HMG-CoA reductase, rosuvastatin or its salt and an excipient of calcium hydrophosphate dihydrate.
EFFECT: technical result: invention provides effective control of blood sugar levels and reduced risk factors of cardiovascular diseases; wherein calcium hydrophosphate dihydrate (trade name DI-TAB, Innophos) plays the role of stabilizer of both active ingredients, gemigliptin (unstable under alkaline conditions) and rosuvastatin (stable in alkaline conditions and unstable in acidic conditions, therefore in usual dosage forms a strong base is often used as its excipient).
11 cl, 2 dwg, 28 tbl
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