METHOD OF PRODUCING INACTIVATED VACCINE AGAINST PULMONARY DISEASES OF YOUNG ANIMALS OF PRODUCTIVE ANIMALS Russian patent published in 2020 - IPC A61K39/09 C12N1/20 C12R1/46 

Abstract RU 2722668 C1

FIELD: biotechnology; medicine.

SUBSTANCE: invention refers to biotechnology and veterinary medicine. Disclosed is a method of producing an inactivated vaccine against pulmonary diseases of young animals of productive animals. Method includes Streptococcus pneumonia cultivation in nutrient medium at initial concentrations of microorganisms 4–7 billion m.t./cm3, at pH 6.8–7.24, limiting growth of streptococci glucose; oxidation-reduction potential of culture liquid −200 ÷ −150 mV and pO2 – 5–25 % of saturation with air oxygen. Streptococcus pneumonia culture is inactivated by formaldehyde with final concentration of 0.03–0.07 % at 41–45 °C for 3–5 days, then an adjuvant - aluminium hydroxide is added.

EFFECT: invention provides higher quality of vaccine for protection of young stock of productive animals against pulmonary diseases.

1 cl, 1 tbl, 6 ex

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RU 2 722 668 C1

Authors

Shkolnikov Efim Emanuilovich

Samujlenko Anatolij Yakovlevich

Anisimova Lyubov Viktorovna

Glushenkova Yuliya Aleksandrovna

Grin Svetlana Anatolevna

Matveeva Irina Nikolaevna

Krasochko Petr Albinovich

Eremets Vladimir Ivanovich

Dates

2020-06-02Published

2019-06-20Filed