ORGAN-SPECIFIC BIOPLASTIC MATERIAL BASED ON SOLUBLE FORM OF STABILIZED EXTRACELLULAR MATRIX Russian patent published in 2020 - IPC A61L27/44 A61L27/24 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to tissue engineering, combustiology, transplantology, cosmetology, and discloses a bioplastic porous material based on a soluble form of a stabilized extracellular matrix. Bioplastic material is characterized by that it has thickness of 0.1–3 cm, is maximally close to physiological parameters of skin derma, consists of three-molecule crossed strands of extracellular matrix and is enriched with a composition containing type I collagen, hyaluronic acid, elastin, as well as biologically active components representing human neonatal fibroblasts in DMEM medium with addition of FBS, L-glutamine, penicillin, streptomycin. Biomaterial has biological compatibility, increasing proliferative potential of cells, enabling organ-specific tissue repair and can act as a biodegradable scaffold.

EFFECT: bioplastic material can be used as biomaterial for stimulation of regeneration and replacement of defects of investing tissues.

1 cl, 2 dwg