COMPOUNDS OF A METABOLITE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST AND A NEP INHIBITOR, AND METHODS FOR PREPARING THEM Russian patent published in 2020 - IPC C07D403/10 C07C231/12 C07C233/47 A61K31/216 A61K31/41 A61P9/00 

Abstract RU 2723642 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to double-action supramolecular complexes (compounds), which have the effect of blocking angiotensin II (AT1), neprilysin inhibitors (NEPi) and represent the compound (EXP3174·AHU377)·1,5Ca·2H2O and (EXP3174·AHU377)·1,5Ca·2,5H2O.

EFFECT: disclosed are compounds of a metabolite of an angiotensin II receptor antagonist and an NEPi inhibitor, and methods of producing said compounds.

10 cl, 7 tbl, 9 ex, 8 dwg

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RU 2 723 642 C1

Authors

Yan Jie

Xu Wenjie

Zhi Jianqiong

Li Song

Wang Yang

Zheng Yanxin

Dates

2020-06-17Published

2017-01-19Filed