COMPOSITIONS AND METHODS FOR TREATING IMMUNODEFICIENCY Russian patent published in 2020 - IPC A61K39/42 A61K45/06 A61P11/00 C07K16/08 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions refers to treating immunodeficiency. Immunotherapeutic composition comprises combined plasma samples obtained from 1000 or more plasma donors, said composition being characterized by a final titre of RSV neutralizing antibodies, of at least 1800 and an antibody titre to one or more respiratory pathogens selected from parainfluenza virus 1, parainfluenza virus 2, coronavirus OC43, coronavirus 229E, influenza A virus, influenza virus B and metapneumovirus, which is at least 1.5 times greater than the titre of said antibodies in the control sample, wherein said control sample is a mixture of plasma samples obtained from 1000 or more random plasma donors, and wherein less than 50 % of pooled plasma samples in said immunotherapeutic composition are obtained from human plasma donors with a final titre of RSV neutralizing antibodies of at least 1800. Also disclosed is a method for providing an immunotherapy for an individual for treating or preventing a respiratory infection and a method of producing the composition.

EFFECT: group of inventions provides an effective immunotherapy.

21 cl, 16 dwg, 19 tbl, 6 ex