PHARMACEUTICAL COMPLEX COMPOSITION CONTAINING AMLODIPINE, LOSARTAN AND ROSUVASTATIN Russian patent published in 2020 - IPC A61K31/4178 A61K31/4422 A61K31/505 A61K47/38 A61K47/26 A61K47/00 A61K9/24 A61J3/10 A61P9/00 

Abstract RU 2724338 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: described are pharmaceutical compositions for preventing or treating a cardiovascular disease comprising amlodipine, rosuvastatin and losartan, and a pharmaceutical complex composition, including a first mixture containing amlodipine and rosuvastatin, and a second mixture containing losartan.

EFFECT: composition and complex composition include rosuvastatin having particle size (D90) of 50 mcm or less, and exhibit an excellent dissolution rate, bioavailability, stability and uniformity of the content, and can therefore be useful in the pharmaceutical industry.

9 cl, 6 tbl, 5 dwg

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RU 2 724 338 C2

Authors

Kim, Yong Il

Im, Ho Taek

Cho, Hyuk Jun

Yoon, Youngsu

Park, Jae Hyun

Woo, Jong Soo

Dates

2020-06-23Published

2016-06-29Filed