ISOXAZOLE DERIVATIVES HAVING ANTIAGGREGATORY ACTIVITY Russian patent published in 2020 - IPC C07D413/04 C07D413/14 A61K31/4439 A61P7/02 

Abstract RU 2726127 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the field of bioorganic and medical chemistry and pharmacology and can be used for development of new antiaggregatory drugs. Disclosed is use of compounds of general formula (values of substitutes are specified in cl. 1 of the invention) as antiaggregatory agents. Invention also relates to isoxazole derivatives: 5-(3-methylbutyl)-3-(3-pyridyl)-4,5-dihydroisoxazole, 5-(2-naphthyl)-3-(3-pyridyl)-4,5-dihydroisoxazole, 5-(7-(N,N-diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-3-(3-pyridyl)-4,5-dihydroisoxazole, 3-(3-pyridyl)-5-cyclohexylisoxazole and 5-(2-naphthyl)-3-(3-pyridyl) isoxazole.

EFFECT: technical result is the use of isoxazole derivatives as antiaggregatory agents.

2 cl, 2 tbl, 8 ex, 3 dwg

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RU 2 726 127 C1

Authors

Demina Olga Viktorovna

Belikov Nikolaj Evgenevich

Varfolomeev Sergej Dmitrievich

Khodonov Andrej Aleksandrovich

Dates

2020-07-09Published

2019-08-20Filed