FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to 5-(4'-hydroxyphenyl)- and 5-(2',5'-dihydroxyphenyl)-6H-1,3,4-thiadiazine-2-amines, hydrohalogenides of general formulas 
and 
inhibiting thrombocyte aggregation in the intravenous introduction NR1R1-morpholino-; thiomorpholino-; pyrrolidino-; piperidino-; hexamethyleneimino-, HHal - HCl; HBr.
EFFECT: given compounds may be used for preparing cardiologic drugs and enable better treatment of various cardiovascular diseases, including myocardial infarction and thrombotic apoplexy.
1 cl, 6 tbl, 2 dwg, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
RU2379306C1 |
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|
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|
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|
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| 2-CYCLOALKYLIMINO-5-(4-NITROPHENYL)-1,3,4-THIADIAZINES POSSESSING BIOLOGICAL ACTIVITY AGAINST SMALLPOX VIRUS | 2005 |
|
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| SUBSTITUTED 6H-1,3,4-THIADIAZINE-2-AMINES, THEIR USE AS ANESTHETIC, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF | 1995 |
|
RU2157210C2 |
| PHARMACEUTICALLY ACCEPTABLE SALTS OF SUBSTITUTED 6H-1,3,4- -THIADIAZINE-2-AMINES AND THEIR PHARMACEUTICAL COMPOSITIONS | 1995 |
|
RU2152943C1 |
| 1-(3-MORPHOLINOPROPYL)-2-PHENYLIMIDAZO[1,2-a]-BENZIMIDAZOLE DIHYDROCHLORIDE, HAVING PURINE P2Y-RECEPTOR ANTAGONIST PROPERTIES, ANTIAGGREGANT AND ANTITHROMBOTIC ACTIVITY | 2008 |
|
RU2391345C2 |
| 2-(1S,2R,5S)-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2YL]METHYL}THIONYL)ETHANOIC ACID, HAVING ANTIAGGREGANT ACTION | 2013 |
|
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| USE OF PINANYLSULFIDE WITH METHYL MERCAPTOACETATE FRAGMENT - METHYL 2-({[(1S,2R,5S)-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]METHYL}THIO) ACETATE, AS AN AGENT WITH INHIBITORY EFFECT ON PLATELET ACTIVATION | 2015 |
|
RU2671567C2 |
