FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a method of producing 3,16,19-trioxahexacyclo[10.5.3.02,4.02,11.015,17.018,20]icos-13-ene. Method involves interaction tricyclo[9.4.2.02,10]geptadeka-2,12,14,16-tetraene (C17H22) with m-chloroperoxybenzoic acid (m-CPBA) in molar ratio C17H22:m-CPBA=2:(10–20) at 0–40 °C in dichloromethane for 3–23 hours. Invention also relates to 3,16,19-trioxahexacyclo[10.5.3.02,4.02,11.015,17.018,20]icos-13-ene, exhibiting anti-tumor activity.
EFFECT: disclosed is a method of producing 3,16,19-trioxahexacyclo[10_5_3_02,4_02,11_015,17_018,20]icos-13-ene, exhibiting antitumour activity.
2 cl, 2 tbl, 2 ex
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Authors
Dates
2020-07-13—Published
2019-02-18—Filed