VARIANTS OF FC-REGION WITH MODIFIED ABILITY TO BIND TO FCRN AND WITH PRESERVED ABILITY TO BIND WITH PROTEIN A Russian patent published in 2020 - IPC C12P21/08 C07K16/22 A61K39/00 

Abstract RU 2727639 C2

FIELD: immunology.

SUBSTANCE: there are presented methods for producing a polypeptide which specifically binds to staphylococcus protein A and does not bind to human FcRn containing four polypeptides.

EFFECT: disclosed invention can find further application in producing polypeptides with reduced clearance and longer half-life.

11 cl, 45 tbl, 20 dwg, 8 ex

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RU 2 727 639 C2

Authors

Shkolaut Aleksander

Shlotauer Tilman

Dates

2020-07-22Published

2015-01-12Filed