MODIFIED IGG ANTIBODIES WHICH BIND TO A TRANSFORMING GROWTH FACTOR BETA-1 WITH HIGH AFFINITY, AVIDITY AND SPECIFICITY Russian patent published in 2020 - IPC C07K16/22 C12N15/09 C12N5/10 A61K39/395 A61P19/08 A61P35/00 

Abstract RU 2728858 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a protein which specifically binds to TGFβ1, and can be used in medicine. TGFβ1 binding protein, is an IgG or Fab-fragment of IgG and can be used for therapeutic and diagnostic purposes.

EFFECT: modified IgG antibodies which bind to a transforming growth factor beta-1 with high affinity, avidity and specificity.

13 cl, 9 dwg, 7 tbl, 6 ex

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RU 2 728 858 C2

Authors

Qiu, Huawei

Bird, Julie

Dates

2020-07-31Published

2016-03-03Filed