ELECTRICALLY ACTIVE HYDROPHILIC BIOPOLYMERS Russian patent published in 2020 - IPC C08F2/44 C08F226/10 A61L27/16 A61L27/50 A61N1/36 C08F220/40 C08F220/44 

Abstract RU 2729643 C2

FIELD: biochemistry.

SUBSTANCE: present invention relates to a method of forming a cross-linked electron-active hydrophilic copolymer, a homogeneous, isotropic, electron-active, hydrophilic copolymer and a solution of comonomers, used for its production. Method comprises the following steps: providing a comonomer solution containing at least one hydrophobic monomer, at least one hydrophilic monomer, water, at least one amino acid and at least one cross-linking agent; and polymerisation of said solution of comonomers. Hydrophilic monomer is selected from methacrylic acid, 2-hydroxyethyl methacrylate, ethyl acrylate, vinylpyrrolidone, methyl ether of acrylic acid, monomethacryloyloxyethyl phthalate, ammonium sulphatoethylmethacrylate, polyvinyl alcohol or a combination thereof. Hydrophobic monomer is selected from methyl methacrylate, allyl methacrylate, acrylonitrile, methacryloxypropyltris(trimethylsiloxy)silane, 2,2,2-trifluoroethyl methacrylate or combinations thereof. At least one amino acid is selected from phenylalanine, tryptophan, histidine, ethylenediaminetetraacetic acid (EDTA) and tyrosine or a combination thereof.

EFFECT: obtained electronically active cross-linked hydrophilic copolymer is suitable for use in biomedical purposes due to its biological acceptability, hydrophilic properties, flexibility and resistance to chemical degradation.

18 cl, 9 dwg, 4 tbl, 6 ex

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RU 2 729 643 C2

Authors

Khajgejt, Donald Dzhejms

Dates

2020-08-11Published

2016-11-30Filed