FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to polymyxin derivatives of formula (I), where groups -A-, -R1, -R2, -R3, -R4, -R5, -R6, -R7, -R8 and -X- are specified in the patent claim, which are intended for treating a bacterial infection.
EFFECT: disclosed are polymyxin derivatives and use thereof in a combined therapy together with various antibiotics.
16 cl, 3 dwg, 18 tbl, 50 ex
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