FIELD: biotechnology.
SUBSTANCE: present invention relates to biotechnology and enables to determine substrate compatibility of properties of 2'-deoxyuridine-5`-triphosphate derivatives and matrix-dependent DNA polymerases.
EFFECT: invention can be used in producing modified DNA fragments, as well as in producing highly efficient modified aptamers by SELEX method.
9 cl, 2 dwg, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DETERMINING SUBSTRATE COMPATIBILITY OF MODIFIED DEOXYURIDINE TRIPHOSPHATE AND DNA POLYMERASE BY COMBINING QUANTITATIVE PCR AND ELECTROPHORESIS METHODS | 2019 |
|
RU2736969C1 |
| METHOD FOR ENZYMATIC PRODUCTION OF MODIFIED DNA FOR PRODUCING REAGENTS WHICH SPECIFICALLY BIND TO HYDROPHOBIC AREAS OF HIGH MOLECULAR WEIGHT ORGANIC COMPOUNDS | 2017 |
|
RU2699522C2 |
| METHOD OF PRODUCING MODIFIED COMBINATORIAL DNA LIBRARIES BY SOLID-PHASE PRIMER EXTENSION REACTION ON PET MICROPARTICLES | 2018 |
|
RU2734941C2 |
| METHOD FOR EVALUATING THE EFFECT OF MODIFIED DEOXYNUCLEOSIDE TRIPHOSPHATES ON THE OLIGONUCLEOTIDE COMPOSITION OF COMBINATORIAL DNA LIBRARIES FOR SELECTING MODIFIED APTAMERS | 2021 |
|
RU2779058C1 |
| THERMAL DISSOCIATION METHOD FOR SELECTION OF DNA-APTAMERS | 2019 |
|
RU2723373C1 |
| METHOD FOR AMPLIFICATION OF NUCLEIC ACIDS USING PHOSPHORYL-GUANIDINE OLIGONUCLEOTIDES | 2017 |
|
RU2698134C2 |
| FLUORESCENTLY-LABELED DEOXYURIDINE TRIPHOSPHATES | 2016 |
|
RU2637310C1 |
| METHOD FOR DETERMINATION OF NUCLEIC ACID MOLECULE SEQUENCE CHARACTERISTICS VIA DETECTION AND CHARACTERIZATION OF SAID SEQUENCE VARIATIONS | 1998 |
|
RU2264468C2 |
| ANALOGUES OF NATURAL DEOXYRIBONUCLEOSIDE TRIPHOSPHATES AND RIBONUCLEOSIDE TRIPHOSPHATES CONTAINING REPORTER FLUORESCENT GROUPS, FOR USE IN ANALYTICAL BIOORGANIC CHEMISTRY | 2014 |
|
RU2582198C1 |
| ENZYMATIC SYNTHESIS OF L-NUCLEIC ACIDS | 2013 |
|
RU2704833C2 |
