FIELD: medicine.
SUBSTANCE: invention refers to medicine, and concerns using compound of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol orally for treating melanoma B16, Ehrlich tumors, sarcoma 180, sarcoma 37, lymphosarcoma LIO-1 and carcinosarcoma Walker 256 experimentally in mice and rats.
EFFECT: invention extends range of agents for treating malignant tumors.
1 cl, 9 ex, 14 dwg, 22 tbl
Title | Year | Author | Number |
---|---|---|---|
APPLICATION OF COMPOUND 2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1.3-PROPANEDIOL FOR TREATMENT OF EHRLICH CARCINOMA, SARCOMA 37, LIO-1 LYMPHOSARCOMA, MELANOMA B16, TRANSPLANTED INTO LOWER EYELID OF MICE IN EXPERIMENT | 2020 |
|
RU2752083C1 |
USE OF THE COMPOUND 2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1,3-PROPANEDIOL FOR TREATING HER2-POSITIVE TUMORS EXPERIMENTALLY | 2018 |
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RU2695787C1 |
METHOD OF SYNTHESIS 2-[3-(2-CHLORETHYL)-3-NITROSOUREIDO]-1,3-PROPANE-DIOL OWNED WITH ANTITUMOR ACTIVITY | 2018 |
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RU2678846C1 |
USE OF THE COMPOUND 2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1,3-PROPANEDIOL IN TREATING MALIGNANT EYE SOCKET TUMOURS IN EXPERIMENT IN MICE WITH TRANSPLANTED INTRAORBITAL EHRLICH CARCINOMA | 2023 |
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RU2815639C1 |
2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1,3-PROPANEDIOL SHOWING ANTITUMOR ACTIVITY | 1992 |
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5-OXYMETHYL-5-[3-(2-CHLORETHYL)-3- NITROZOUREIDO]-2-CYCLOHEXYL- 1 | 2000 |
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DIHYDROCHLORIDE 1-(3-NITRO-4- METHOXYBENZENE)-2- [BIS-(2- CHLORETHYL) AMINOMETHYL]IMIDAZOLE POSSESSING ANTITUMOR ACTIVITY | 1981 |
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4(5)-(3-NITRO-4-(3,3-DIMETHYLTRIAZENO-1)PHENYL)IMIDAZOLE POSSESSING ANTITUMOR ACTIVITY | 1982 |
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SU1074091A1 |
1-(4-AMYLHYDROXY-3-NITROBENZYL)-2-METHYL-4-NITRO-5-[BIS-(2- CHLOROETHYL)-AMINOETHYL]-THIOIMIDAZOLE HYDROCHLORIDE SHOWING ANTITUMOR ACTIVITY | 1985 |
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MEDICINAL PREPARATION POSSESSING ANTITUMOR ACTIVITY | 1988 |
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Authors
Dates
2020-10-05—Published
2020-03-24—Filed