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2 815 639

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IPC

A61K31/175(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2023118369, 2023-07-11

(24)

Start date

2023-07-11

(22)

Actual filing date

2023-07-11

(45)

Published

2024-03-19

(72)

Inventor

Zmitrichenko Yuliya GennadevnaStukov Aleksandr NikolaevichKharitonova Natalya NikolaevnaKulikov Aleksej NikolaevichKoroleva Anastasiya FilippovnaAleksandrov Valerij AnatolevichPoltoratskij Artem NikolaevichZhilinskaya Nadezhda TarasovnaVasileva Olesya AleksandrovnaSemiglazova Tatyana YurevnaFilatova Larisa ValentinovnaLatipova Dilorom KhamidovnaVershinina Sofiya FatkhutdinovnaNyuganen Anna OlegovnaIvantsov Aleksandr OlegovichArtemeva Anna SergeevnaSenchik Konstantin YurevichSuslov Dmitrij NikolaevichTochilnikov Grigorij Viktorovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Onkologii Imeni N.N. Petrova" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

USE OF THE COMPOUND 2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1,3-PROPANEDIOL IN TREATING MALIGNANT EYE SOCKET TUMOURS IN EXPERIMENT IN MICE WITH TRANSPLANTED INTRAORBITAL EHRLICH CARCINOMA Russian patent published in 2024 - IPC A61K31/175 A61P35/00

Abstract RU 2815639 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental oncological ophthalmology, and can be used for treating malignant eye socket tumours in experiment in mice with transplanted intraocular Ehrlich carcinoma. For this purpose, compound 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol is used in a single dose of 20 mg/kg intraperitoneally.

EFFECT: use of compound 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol increases the therapeutic effect in the treatment of mice with transplanted intraocular Ehrlich carcinoma, promotes inhibition of tumour growth and prolongation of life with complete recovery.

1 cl, 7 dwg, 4 tbl, 2 ex

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RU 2 815 639 C1

Authors

Zmitrichenko Yuliya Gennadevna

Stukov Aleksandr Nikolaevich

Kharitonova Natalya Nikolaevna

Kulikov Aleksej Nikolaevich

Koroleva Anastasiya Filippovna

Aleksandrov Valerij Anatolevich

Poltoratskij Artem Nikolaevich

Zhilinskaya Nadezhda Tarasovna

Vasileva Olesya Aleksandrovna

Semiglazova Tatyana Yurevna

Filatova Larisa Valentinovna

Latipova Dilorom Khamidovna

Vershinina Sofiya Fatkhutdinovna

Nyuganen Anna Olegovna

Ivantsov Aleksandr Olegovich

Artemeva Anna Sergeevna

Senchik Konstantin Yurevich

Suslov Dmitrij Nikolaevich

Tochilnikov Grigorij Viktorovich

Dates

2024-03-19—Published

2023-07-11—Filed