ANALYTICAL METHOD FOR IDENTIFYING AT LEAST ONE GLYCOL FORM OF TRANSFERRIN PROTEIN Russian patent published in 2020 - IPC G01N33/58 C07K14/79 

Abstract RU 2734412 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method for identifying at least one glycoform and/or transferrin isoform in various types of complex biological media. To this end, the analyzed biological fluid is brought into contact with lanthanide 3+ ion source. Obtained derivatives of carbohydrate-deficient transferrin with lanthanide ions 3+ are analyzed by HPLC or CE using a fluorescent detector.

EFFECT: invention provides a reliable and sensitive method of determining carbohydrate-deficient transferrin in blood serum, blood plasma, in cerebrospinal fluid, vitreous fluid or saliva for diagnosing the clinical/toxicological state of the patient.

15 cl, 3 dwg, 3 ex

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RU 2 734 412 C2

Authors

De Palo Elio Franko

Tagliaro Franko

Sorio Daniela

Bortolotti Federika

Dates

2020-10-16Published

2015-03-10Filed