FIELD: biotechnology.
SUBSTANCE: disclosed is a method of producing a mammalian cell line which expresses the hormone recombinant horse chorionic gonadotropin (reCG). Invention also describes a cell line expressing reCG, a large-scale method of producing reCG, reCG with higher biological activity compared to PMSG, a composition containing reCG, nucleic acids coding reCG, and use thereof.
EFFECT: invention can be used for ovulation induction in female animals.
27 cl, 14 dwg, 5 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| RECOMBINANT CHORIONIC GONADOTROPIN, A METHOD OF ITS PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | 2019 |
|
RU2803047C1 |
| PLASMID FOR EXPRESSION OF RECOMBINANT HUMAN CHORIONIC GONADOTROPIN (HCG), PLASMID FOR EXPRESSION OF RECOMBINANT ALPHA- AND BETA-SUBUNITS OF HCG, MONOCLONAL LINE OF MAMMALIAN CELLS - PRODUCER OF HCG, METHOD OF PRODUCING RECOMBINANT HCG | 2024 |
|
RU2834784C1 |
| CELL LINE HUFSHKKC6, PRODUCER OF RECOMBINANT HUMAN FOLLICLE STIMULATING HORMONE (FSH) AND METHOD FOR PRODUCING FSH USING SAID LINE | 2018 |
|
RU2694598C1 |
| EXPRESSION PLASMID FOR HUMAN RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) IN CHO CELLS, EXPRESSION PLASMID FOR BETA-SUBUNIT OF HUMAN RECOMBINANT FSH IN CHO CELLS, CHO CELL PRODUCING HUMAN RECOMBINANT FSH, AND METHOD FOR PRODUCING ABOVE HORMONE | 2013 |
|
RU2560596C2 |
| CELL LINE HUFSHIK RELEASING RECOMBINANT HUMAN FOLLICLE-STIMULATING HORMONE | 2012 |
|
RU2502798C2 |
| PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HUMAN CHORIONIC GONADOTROPIN | 2010 |
|
RU2588650C2 |
| PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HCG (HUMAN CHORIONIC GONADOTROPIN HORMONE) | 2010 |
|
RU2724528C2 |
| EXPRESSION PLASMID VECTOR OF MONOCISTRONIC EXPRESSION OF RECOMBINANT PROTEINS IN MAMMALIAN CELLS, CELL LINE OF MAMMALS-PRODUCERS OF RECOMBINANT PROTEIN, METHOD OF OBTAINING RECOMBINANT PROTEIN | 2013 |
|
RU2552170C2 |
| GLYCOPROTEIN HORMONE LONG-ACTING SUPERAGONISTS | 2013 |
|
RU2668174C2 |
| METHOD OF PRODUCING HUMAN RECOMBINANT FOLLICLE-STIMULATING HORMONE, PRODUCING CELL LINE AND PLASMID EXPRESSION VECTORS | 2019 |
|
RU2697273C1 |
