METHOD OF PRODUCING CONDENSED IMIDAZOLE DERIVATIVES Russian patent published in 2020 - IPC C07D487/04 

Abstract RU 2734818 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to a method of producing a compound of formula (I), comprising a step of reacting a compound of formula VII with a base, which is lithium bis(trimethylsilyl)amide, in the presence of a lithium halide, where LG denotes a leaving group, wherein the method is carried out in an aprotic inert solvent at temperature of −100 °C to 0 °C.

EFFECT: method of producing a compound of formula (I), characterized by high output and purity of the desired compound.

9 cl, 1 tbl, 2 ex

Similar patents RU2734818C2

Title Year Author Number
METHODS FOR OBTAINING CYTOTOXIC BENZODIAZEPINE DERIVATIVES 2019
  • Reardon, Majkl
  • Silva, Richard A.
RU2807546C2
OBTAINING INTERMEDIATE PRODUCTS FOR SYNTHESIS OF POSACONAZOLE 2011
  • De-Suza Dominik
  • Joshi Shrirang V.
  • Bkhuta Zachin
  • Pajz Abkhinaj S.
  • Chavan Dattatraja N.
  • Metkar Shashikant D.
RU2580318C2
METHOD OF NEBIVOLOL RACEMATE OBTAINMENT 2006
  • Bader Tomas
  • Shtutts Al'Fred
  • Khofmajer Kharal'D
  • Bikhzel' Khans-Ul'Rikh
RU2392277C2
DERIVATIVES OF CARBOXYLIC ACIDS WITH OXAZOLE[5,4-b]PYRIDINE RING 2012
  • Kaderajt Diter
  • Shefer Mattias
  • Khakhtel Shtefani
  • Khyubshle Tomas
  • Khiss Katrin
RU2609002C2
METHOD OF PRODUCING CHIRAL TRIAZOLONES 2011
  • Oberkhuber Mikhael
  • Zalkhenegger Jorg
  • De-Suza Dominik
  • Albert Martin
  • Vilkhelm Torsten
  • Langner Martin
  • Shturm Khuber
  • Shpittsenshtetter Khans-Peter
RU2585760C2
METHOD FOR PRODUCING SUBSTITUTED 3-PYRIDYLMETHYL AMMONIUM BROMIDES 2009
  • Joakhim Gebkhardt
  • Frederik Menges
  • Mikhaehl' Rakk
  • Mikhaehl' Kajl'
  • Jokhen Shreder
  • Shtefan Orsten
  • Khel'Mut Tsekh
  • Rodni F Klima
  • Dejvid Kortes
  • Robert Lekht
  • Toni Jegerlener
RU2549896C2
METHOD OF PRODUCING DIARYL CYCLOALKYL DERIVATIVES 2005
  • Salan'Ja Kristof
  • Tsokher Frank
  • Burgard Andreas
  • Junker Bernd
  • Kherljajn Rol'F
  • Shtjudemann Tomas
  • Majer Klaus-Jurgen
  • Khakhtel' Jokhen
  • Kholla Vol'Fgang
  • Tapperttskhofen Kristof
  • Kulittssher Berndt
  • Mjutti Stefan
RU2414459C2
METHOD OF PRODUCING COMPOUND USED AS TAFIa INHIBITOR 2010
  • Rossen Kaj
  • Kraft Fol'Ker
  • Velan Khermut
  • Bigo Antoni
  • Krok-Stjuehrga Veronik
RU2538506C2
DERIVATIVES OF CARBOXYLIC ACIDS WITH OXAZOLE[4,5-c]PYRIDINE CYCLE 2012
  • Kaderajt Diter
  • Shefer Mattias
  • Khakhtel Shtefani
  • Khyubshle Tomas
  • Khiss Katrin
RU2609004C2
METHODS AND COMPOUNDS THAT CAN BE USED TO SYNTHESIZE OREXIN-2 RECEPTORS ANTAGONISTS 2013
  • Moniz Dzhordzh Entoni
  • Uilkoksen Enni Zhu
  • Benajud Farid
  • Li Dzaemoon
  • Chzhan Khojmin
  • Terauti Taro
  • Takemura Ayumi
  • Josida Yu
  • Tanaka Tosiaki
  • Sorimati Keiiti
  • Naoe Josimitsu
  • Kadzuta Yudzi
RU2617696C2

RU 2 734 818 C2

Authors

Shilling Khanspeter

Bertogg Andreas

Dates

2020-10-23Published

2016-01-28Filed