VELDORETID, HAVING POOR SOLUBILITY IN PHYSIOLOGICAL CONDITIONS, FOR USE IN TREATING ACROMEGALY, ACROMEGALY WITH MALIGNANT GROWTH, EXPRESSING SST-R5 TUMORS, TYPE 2 DIABETES, HYPERGLYCEMIA AND TUMORS ASSOCIATED WITH HORMONES Russian patent published in 2020 - IPC A61K38/27 A61P3/10 A61P35/00

Abstract RU 2736590 C2

FIELD: medicine; oncology.

SUBSTANCE: present group of inventions concerns treating tumors expressing SST-R5. That is ensured by administering an effective amount of the pharmaceutical composition containing the veldoreotid or its pharmaceutically acceptable salt encapsulated in the polymer microsphere, and an excipient selected from hydroxypropyl-β-cyclodextrin (HPBCD) or dextrose.

EFFECT: introduction of such composition provides effective treatment with reduced side effects due to higher solubility and bioavailability of the drug.

28 cl, 26 tbl, 7 ex, 29 dwg

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RU 2 736 590 C2

Authors

Afargan, Majkl

Dates

2020-11-18—Published

2017-02-16—Filed