FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to the field of medicine and pharmaceutics and represents pharmaceutical compositions (4 embodiments) comprising a compound of formula I:
,
where R is selected from a group consisting of phenyl, 4-benzyloxyphenyl, 4-biphenyl, 4-methoxyphenyl, 3-methoxyphenyl, 2-methoxyphenyl, 3,5-dimethoxyphenyl, 4-chlorophenyl, 3-chlorophenyl, 2-chlorophenyl, 4-methylphenyl, 3-methylphenyl, 2-methylphenyl and 3-trifluoromethylphenyl, or a salt thereof; and water-soluble beta-cyclodextrin.
EFFECT: group of inventions provides higher solubility of said compounds, thereby increasing oral bioavailability.
21 cl, 5 dwg, 19 tbl, 13 ex
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