FIELD: pharmaceuticals.
SUBSTANCE: invention concerns a tablet containing candesartan or candesartan cilexetil and amlodipine or its pharmaceutically acceptable salt as active ingredients. In addition to said combination of active substances, the declared tablet also contains macrogol-15-hydroxystearate as a solubilising agent.
EFFECT: use of the disclosed solubilizer in the tablet provides higher stability of the active substances for a long storage period, as well as improved solubility of the tablet in the gastrointestinal tract or digestive tract of the body, which enables to maintain the level of the drug in the blood at a constant level.
8 cl, 16 ex, 12 tbl
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Authors
Dates
2020-11-23—Published
2016-12-28—Filed